Newly identified monogenic entities such as DADA2 (deficiency of adenosine deaminase 2) and VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome also exhibit vasculitic features and are associated with a high risk of thrombosis
Such strategies are initiated in several laboratories and if successful, they could constitute at longterm an alternative to intracytoplasmic sperm injection by directly treating infertile men
Klusa VZ, Isajevs S, Svirina D, Pupure J, Beitnere U, Rumaks J, Svirskis S, Jansone B, Dzirkale Z, Muceniece R, Kalvinsh I, Vinters HV (2010) Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease
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